Deregulated proliferation and differentiation in brain tumors
نویسندگان
چکیده
منابع مشابه
Deregulated KLF4 Expression in Myeloid Leukemias Alters Cell Proliferation and Differentiation through MicroRNA and Gene Targets.
Acute myeloid leukemia (AML) is characterized by increased proliferation and blocked differentiation of hematopoietic progenitors mediated, in part, by altered myeloid transcription factor expression. Decreased Krüppel-like factor 4 (KLF4) expression has been observed in AML, but how decreased KLF4 contributes to AML pathogenesis is largely unknown. We demonstrate decreased KLF4 expression in A...
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ژورنال
عنوان ژورنال: Cell and Tissue Research
سال: 2014
ISSN: 0302-766X,1432-0878
DOI: 10.1007/s00441-014-2046-y